Focusing light inside scattering media with magnetic-particle-guided wavefront shaping.

ABSTRACT: Optical scattering has traditionally limited the ability to focus light inside scattering media such as biological tissue. Recently developed wavefront shaping techniques promise to overcome this limit by tailoring an optical wavefront to constructively interfere at a target location deep inside scattering media. To find such a wavefront solution, a "guide-star" mechanism is required to identify the target location. However, developing guidestars of practical usefulness is challenging, especially in biological tissue, which hinders the translation of wavefront shaping techniques. Here, we demonstrate a guidestar mechanism that relies on magnetic modulation of small particles. This guidestar method features an optical modulation efficiency of 29% and enables micrometer-scale focusing inside

SUBMITTER: Ruan H 

PROVIDER: S-EPMC5881932 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature