The constitutive differential transcriptome of a brain circuit for vocal learning.

ABSTRACT:

Background

The ability to imitate the vocalizations of other organisms, a trait known as vocal learning, is shared by only a few organisms, including humans, where it subserves the acquisition of speech and language, and 3 groups of birds. In songbirds, vocal learning requires the coordinated activity of a set of specialized brain nuclei referred to as the song control system. Recent efforts have revealed some of the genes that are expressed in these vocal nuclei, however a thorough characterization of the transcriptional specializations of this system is still missing. We conducted a rigorous and comprehensive analysis of microarrays, and conducted a separate analysis of 380 genes by in situ hybridizations in order to identify molecular specializations of the major nuclei of the s

SUBMITTER: Lovell PV 

PROVIDER: S-EPMC5883274 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature