First molecular detection and characterization of Marek's disease virus in red-crowned cranes (Grus japonensis): a case report.

ABSTRACT:

Background

Marek's disease virus (MDV) resides in the genus Mardivirus in the family Herpesviridae. MDV is a highly contagious virus that can cause neurological lesions, lymphocytic proliferation, immune suppression, and death in avian species, including Galliformes (chickens, quails, partridges, and pheasants), Strigiformes (owls), Anseriformes (ducks, geese, and swans), and Falconiformes (kestrels).

Case presentation

In 2015, two red-crowned cranes died in Nanjing (Jiangsu, China). It was determined that the birds were infected with Marek's disease virus by histopathological examination, polymerase chain reaction (PCR), gene sequencing and sequence analysis of tissue samples from two cranes. Gross lesions included diffuse nodules in the skin, muscle, liver, spleen, kidney,

SUBMITTER: Lian X 

PROVIDER: S-EPMC5883596 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature