Cinnamomum burmanini Blume increases bone turnover marker and induces tibia's granule formation in ovariectomized rats.

ABSTRACT: BACKGROUND:Bone fragility and an increase in susceptibility to fracture osteoporosis is characterized by a reduction in bone mass and the micro-architectural deterioration of bone tissue. There is no previous study regarding the effect of Cinnamomum burmanini Blume on osteoporosis. OBJECTIVE:This study was aimed to investigate the effect of C. burmanini Blume on bone turnover marker, mineral elements, and mesostructure of ovariectomized rats. MATERIALS AND METHODS:Thirty female Wistar rats were randomly divided into five groups, which included a control group (sham surgery), ovariectomy group (OVX), and ovariectomy groups in the presence of ethanolic extract of C. burmanini Blume (EECB) at doses of 12.5; 25; 50 mg/kg body weight (BW). Analysis of serum C-telopeptide collagen type I (CTX) a

SUBMITTER: Kania N 

PROVIDER: S-EPMC5884038 | biostudies-literature | 2018 Jan - Mar

REPOSITORIES: biostudies-literature