Thyroid disorders and breast cancer risk in Asian population: a nationwide population-based case-control study in Taiwan.

ABSTRACT: OBJECTIVE:To evaluate whether hyperthyroidism or hypothyroidism increases the risk of subsequent breast cancer in an Asian population. DESIGN:Nationwide population-based case-control study. SETTING:All healthcare facilities in Taiwan. PARTICIPANTS:A total of 103 466 women (mean age 53.3 years) were enrolled. METHODS:51 733 adult women with newly diagnosed primary breast cancer without a previous cancer history between 2006 and 2011 were identified and included in our study. 51 733 women with no cancer diagnosis prior to the index date were age matched as controls. Diagnosis of hyperthyroidism or hypothyroidism prior to the diagnosis of breast cancer or the same index date was identified, age, histories of thyroid disease treatment, oestrogen use and radioactive iodine treatment were adjust

SUBMITTER: Weng CH 

PROVIDER: S-EPMC5884336 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature