Dementia and vagotomy in Taiwan: a population-based cohort study.

ABSTRACT: OBJECTIVE:Truncal vagotomy is associated with a decreased risk of subsequent Parkinson disease (PD), although the effect of vagotomy on dementia is unclear. In response, we investigated the risk of dementia in patients who underwent vagotomy. SETTING:Population-based cohort study. PARTICIPANTS:A total of 155 944 patients who underwent vagotomy (vagotomy cohort) and 155 944 age-matched, sex-matched and comorbidity-matched controls (non-vagotomy cohort) were identified between 2000 and 2011. PRIMARY AND SECONDARY OUTCOME MEASURES:All patient data were tracked until the diagnosis of dementia, death or the end of 2011. The cumulative incidence of subsequent dementia and HRs were calculated. RESULTS:The mean ages of the study patients in the vagotomy and non-vagotomy cohorts were 56.6±17.4 and

SUBMITTER: Lin SY 

PROVIDER: S-EPMC5884346 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature