Circulating Levels of Inflammatory Proteins and Survival in Patients with Gallbladder Cancer.

ABSTRACT: Although inflammation is central to gallbladder cancer (GBC) development and proliferation, no study has systematically investigated circulating inflammatory proteins and patient survival. We aimed to examine whether the circulating levels of inflammatory proteins is associated with all-cause mortality among such patients. We recruited 134 patients with newly diagnosed with GBC from 1997 to 2001 in a population-based study in Shanghai and an independent set of 35 patients from 2012 to 2013 in Chile. Cox proportional hazards regression models adjusted for covariates were used to evaluate the hazard ratios (HRs) for death by serum levels of 49 inflammatory proteins (quartiles). Of 49 evaluable proteins, eight were significantly associated with overall survival. Seven were associated with a p

SUBMITTER: Liu Z 

PROVIDER: S-EPMC5884817 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature