Association of Reperfusion With Brain Edema in Patients With Acute Ischemic Stroke: A Secondary Analysis of the MR CLEAN Trial.

ABSTRACT:

Importance

It is uncertain whether therapeutic reperfusion with endovascular treatment yields more or less brain edema.

Objective

To elucidate the association between reperfusion and brain edema. The secondary objectives were to evaluate whether brain edema could partially be responsible for worse outcomes in patients with later reperfusion or lower Alberta Stroke Program Early Computed Tomography Score.

Design, setting, and participants

This was a post hoc analysis of the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands (MR CLEAN), which was a prospective, randomized, multicenter clinical trial of endovascular treatment compared with conventional care of patients with acute anterior circulation ischemic stro

SUBMITTER: Kimberly WT 

PROVIDER: S-EPMC5885187 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature