Association of Time to Treatment With Short-term Outcomes for Pediatric Patients With Refractory Convulsive Status Epilepticus.

ABSTRACT:

Importance

Treatment delay for seizures can lead to longer seizure duration. Whether treatment delay is associated with major adverse outcomes, such as death, remains unknown.

Objective

To evaluate whether untimely first-line benzodiazepine treatment is associated with unfavorable short-term outcomes.

Design, setting, and participants

This multicenter, observational, prospective cohort study included 218 pediatric patients admitted between June 1, 2011, and July 7, 2016, into the 11 tertiary hospitals in the United States within the Pediatric Status Epilepticus Research Group. Patients, ranging in age from 1 month to 21 years, with refractory convulsive status epilepticus (RCSE) that did not stop after the administration of at least 2 antiseizure medications were incl

SUBMITTER: Gainza-Lein M 

PROVIDER: S-EPMC5885266 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature