A computational reconstruction of Papio phylogeny using Alu insertion polymorphisms.

ABSTRACT:

Background

Since the completion of the human genome project, the diversity of genome sequencing data produced for non-human primates has increased exponentially. Papio baboons are well-established biological models for studying human biology and evolution. Despite substantial interest in the evolution of Papio, the systematics of these species has been widely debated, and the evolutionary history of Papio diversity is not fully understood. Alu elements are primate-specific transposable elements with a well-documented mutation/insertion mechanism and the capacity for resolving controversial phylogenetic relationships. In this study, we conducted a whole genome analysis of Alu insertion polymorphisms unique to the Papio lineage. To complete t

SUBMITTER: Jordan VE 

PROVIDER: S-EPMC5885306 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature