Association of Preoperative and Postoperative Serum Carcinoembryonic Antigen and Colon Cancer Outcome.

ABSTRACT:

Importance

Guidelines recommend measuring preoperative carcinoembryonic antigen (CEA) in patients with colon cancer. Although persistently elevated CEA after surgery has been associated with increased risk for metastatic disease, prognostic significance of elevated preoperative CEA that normalized after resection is unknown.

Objective

To investigate whether patients with elevated preoperative CEA that normalizes after colon cancer resection have a higher risk of recurrence than patients with normal preoperative CEA.

Design, setting, and participants

This retrospective cohort analysis was conducted at a comprehensive cancer center. Consecutive patients with colon cancer who underwent curative resection for stage I to III colon adenocarcinoma at the center from January

SUBMITTER: Konishi T 

PROVIDER: S-EPMC5885834 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature