Association Between Fluid Balance and Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis.

ABSTRACT: Importance:After initial resuscitation, critically ill children may accumulate fluid and develop fluid overload. Accruing evidence suggests that fluid overload contributes to greater complexity of care and worse outcomes. Objective:To describe the methods to measure fluid balance, define fluid overload, and evaluate the association between fluid balance and outcomes in critically ill children. Data Sources:Systematic search of MEDLINE, EMBASE, Cochrane Library, trial registries, and selected gray literature from inception to March 2017. Study Selection:Studies of children admitted to pediatric intensive care units that described fluid balance or fluid overload and reported outcomes of interest were included. No language restrictions were applied. Data Extraction and Synthesis:All stages we

SUBMITTER: Alobaidi R 

PROVIDER: S-EPMC5885847 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature