Treatment Outcomes in Patients With Newly Diagnosed Epilepsy Treated With Established and New Antiepileptic Drugs: A 30-Year Longitudinal Cohort Study.

ABSTRACT:

Importance

A study published in 2000 showed that more than one-third of adults with epilepsy have inadequate control of seizures with antiepileptic drugs (AEDs). This study evaluates overall treatment outcomes in light of the introduction of more than 1 dozen new AEDs in the past 2 decades.

Objective

To assess long-term treatment outcome in patients with newly diagnosed and treated epilepsy.

Design, setting, and participants

This longitudinal observational cohort study was conducted at the Epilepsy Unit of the Western Infirmary in Glasgow, Scotland. A total of 1795 individuals who were newly treated for epilepsy with AEDs between July 1, 1982, and October 31, 2012, were included in this analysis. All patients were followed up for a minimum of 2 years (until October 31

SUBMITTER: Chen Z 

PROVIDER: S-EPMC5885858 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature