Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia.

ABSTRACT: Importance:The ability to predict the pathology underlying different neurodegenerative syndromes is of critical importance owing to the advent of molecule-specific therapies. Objective:To determine the rates of positron emission tomography (PET) amyloid positivity in the main clinical variants of primary progressive aphasia (PPA). Design, Setting, and Participants:This prospective clinical-pathologic case series was conducted at a tertiary research clinic specialized in cognitive disorders. Patients were evaluated as part of a prospective, longitudinal research study between January 2002 and December 2015. Inclusion criteria included clinical diagnosis of PPA; availability of complete speech, language, and cognitive testing; magnetic resonance imaging performed within 6 months of the cogni

SUBMITTER: Santos-Santos MA 

PROVIDER: S-EPMC5885868 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature