Serial In-Office Intralesional Steroid Injections in Airway Stenosis.

ABSTRACT:

Importance

Endoscopic dilation is the mainstay treatment strategy for subglottic and proximal tracheal stenosis (SGS/PTS). Its major limitation is restenosis requiring repeated surgery. Intralesional steroid injection (ISI) is a promising adjunctive treatment aimed at prolonging the effects of dilation.

Objective

To evaluate the association of serial in-office ISI after endoscopic dilation with surgery-free interval (SFI) in adults with SGS/PTS.

Design, setting, and participants

A retrospective study of adults with SGS/PTS who underwent at least 2 consecutive in-office ISI at the University of Southern California, Keck School of Medicine, over a 3-year period was conducted.

Exposure

Serial ISI with triamcinolone 40 mg/mL using topical anesthesia, spaced 3 to 6

SUBMITTER: Bertelsen C 

PROVIDER: S-EPMC5885880 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature