Ontology highlight
ABSTRACT:
SUBMITTER: Mesci P
PROVIDER: S-EPMC5886060 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Human molecular genetics 20180101 1
Although Zika virus (ZIKV) infection is often asymptomatic, in some cases, it can lead to birth defects in newborns or serious neurologic complications in adults. However, little is known about the interplay between immune and neural cells that could contribute to the ZIKV pathology. To understand the mechanisms at play during infection and the antiviral immune response, we focused on neural precursor cells (NPCs)-microglia interactions. Our data indicate that human microglia infected with the c ...[more]