Empirical estimation of life expectancy from a linked health database of adults who entered care for HIV.

ABSTRACT:

Background

While combination antiretroviral therapy (cART) has significantly improved survival times for persons diagnosed with HIV, estimation of life expectancy (LE) for this cohort remains a challenge, as mortality rates are a function of both time since diagnosis and age, and mortality rates for the oldest age groups may not be available.

Methods

A validated case-finding algorithm for HIV was used to update the cohort of HIV-positive adults who had entered care in Ontario, Canada as of 2012. The Chiang II abridged life table algorithm was modified to use mortality rates stratified by time since entering the cohort and to include various methods for extrapolation of the excess HIV mortality rates to older age groups.

Results

As of 2012, there were approximately 15,

SUBMITTER: Schanzer D 

PROVIDER: S-EPMC5886421 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature