Gestational Obstructive Sleep Apnea: Biomarker Screening Models and Lack of Postpartum Resolution.

ABSTRACT: STUDY OBJECTIVES:To measure prevalence and severity of third trimester obstructive sleep apnea and evaluate postpartum resolution. To assess a novel biomarker for screening for obstructive sleep apnea in pregnancy. METHODS:This prospective observational study was performed at Wake Forest School of Medicine obstetrics clinics between April 2014 and December 2015. Fractional exhaled nitric oxide measurements and sleep studies were obtained and compared at 32 0/7 to 35 6/7 weeks gestation and postpartum. Exhaled nitric oxide and risk factors for the development of gestational sleep apnea were evaluated for predictive ability independently and in screening models. RESULTS:Of 76 women enrolled, 73 performed valid sleep studies in pregnancy and 65 had an additional valid study 6 to 15 weeks post

SUBMITTER: Street LM 

PROVIDER: S-EPMC5886432 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature