Randomized trial of a clinic-based weight loss intervention in cancer survivors.

ABSTRACT: BACKGROUND:This trial examined the efficacy of a clinic-based weight loss intervention in cancer survivors. METHODS:This single-center phase II trial randomized survivors of solid tumors and hematologic malignancies to a 15-week group-based weight loss intervention that included caloric restriction and physical activity (n = 30) or a wait-list control intervention (n = 30). The primary study outcome was body mass. Secondary study outcomes included body composition using dual-energy X-ray absorptiometry, physical fitness using the 6-min walk test (6MWT), and concentrations of serum biomarkers. RESULTS:Participants in the intervention group lost 5.6 ± 4.4% of baseline weight (4.6 ± 3.9 kg), whereas participants in the control group gained 0.2 ± 2.4% of baseline weight (0.2 ± 2.0 kg); interve

SUBMITTER: Brown JC 

PROVIDER: S-EPMC5886810 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature