Phlebotomine mortality effect of systemic insecticides administered to dogs.

ABSTRACT:

Background

Zoonotic visceral leishmaniasis (ZVL) caused by Leishmania (Leishmania) infantum is an important disease in humans and dogs. Different mammal species are reservoirs but dogs are considered to be the main one. Phlebotomine sand flies are the proven vector. Four systemic insecticides approved for their use in dogs were previously selected based on their potential to be used in endemic countries as part of the control programs of ZVL. These insecticides are proved to be safe and effective against the on-label insects and parasites, but there is no information about their activity against phlebotomine sand flies.

Methods

The phlebotomine mortality of four systemic insecticides in dogs was evaluated using two randomized clinical trials. For the first trial, thirty dogs

SUBMITTER: Gomez SA 

PROVIDER: S-EPMC5887228 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature