Measurement of Vitamin D for Epidemiologic and Clinical Research: Shining Light on a Complex Decision.

ABSTRACT: Vitamin D is a fat-soluble vitamin that is synthesized in the skin with exposure to sunlight or is ingested from dietary supplements or food. There has been a dramatic increase in research on vitamin D, linking it with health outcomes as varied as reproductive function, infection, cardiovascular disease, and cancer. The study of vitamin D has generated much excitement, partly because there is an ideal intervention: Low levels may be common and can be remedied with widely available supplements. Determination of vitamin D status is complex and has advanced dramatically in the past 5 years. In this paper, we begin by describing important considerations for measurement of total 25-hydroxyvitamin D (25(OH)D), the biomarker traditionally assessed in epidemiologic studies. While 25(OH)D remains t

SUBMITTER: Jukic AMZ 

PROVIDER: S-EPMC5889008 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature