Antimony susceptibility of Leishmania isolates collected over a 30-year period in Algeria.

ABSTRACT:

Background

In Algeria, the treatment of visceral and cutaneous leishmanioses (VL and CL) has been and continues to be based on antimony-containing drugs. It is suspected that high drug selective pressure might favor the emergence of chemoresistant parasites. Although treatment failure is frequently reported during antimonial therapy of both CL and VL, antimonial resistance has never been thoroughly investigated in Algeria. Determining the level of antimonial susceptibility, amongst Leishmania transmitted in Algeria, is of great importance for the development of public health policies.

Methodology/principal findings

Within the framework of the knowledge about the epidemiology of VL and CL amassed during the last 30 years, we sampled Leishmania isolates to determine their susc

SUBMITTER: Eddaikra N 

PROVIDER: S-EPMC5889277 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature