Genetic structure, divergence and admixture of Han Chinese, Japanese and Korean populations.

ABSTRACT:

Background

Han Chinese, Japanese and Korean, the three major ethnic groups of East Asia, share many similarities in appearance, language and culture etc., but their genetic relationships, divergence times and subsequent genetic exchanges have not been well studied.

Results

We conducted a genome-wide study and evaluated the population structure of 182 Han Chinese, 90 Japanese and 100 Korean individuals, together with the data of 630 individuals representing 8 populations wordwide. Our analyses revealed that Han Chinese, Japanese and Korean populations have distinct genetic makeup and can be well distinguished based on either the genome wide data or a panel of ancestry informative markers (AIMs). Their genetic structure corresponds well to their geographical distributions, ind

SUBMITTER: Wang Y 

PROVIDER: S-EPMC5889524 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature