Neurodevelopmental assessment of HIV-exposed uninfected and early-treated HIV-infected children: study protocol.

ABSTRACT:

Objective

Sub-Saharan Africa has the highest prevalence of children at risk of not achieving their developmental potential, attributable largely to the human immunodeficiency virus (HIV) pandemic coupled with negative environmental factors. Childhood developmental stimulation programmes can mitigate adverse outcomes.

Methods

Neonates testing HIV positive at birth will be initiated on antiretroviral treatment (ART) and receive an age-appropriate stimulation program, updated at 3 monthly intervals through the first year of life. Neurodevelopment at 12 months of age will be assessed using the Bayley Scales of Infant and Toddler Development, Third Edition (BSID-III). Outcomes will be compared with HIV-infected and HIV-exposed uninfected children (HEU) not having received the sti

SUBMITTER: Strehlau R 

PROVIDER: S-EPMC5889550 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature