Prevalent emm Types among Invasive GAS in Europe and North America since Year 2000.

ABSTRACT:

Background

Streptococcus pyogenes or group A streptococcus (GAS) is an important human pathogen responsible for a broad range of infections, from uncomplicated to more severe and invasive diseases with high mortality and morbidity. Epidemiological surveillance has been crucial to detect changes in the geographical and temporal variation of the disease pattern; for this purpose the M protein gene (emm) gene typing is the most widely used genotyping method, with more than 200 emm types recognized. Molecular epidemiological data have been also used for the development of GAS M protein-based vaccines.

Methods

The aim of this paper was to provide an updated scenario of the most prevalent GAS emm types responsible for invasive infections in developed co

SUBMITTER: Gherardi G 

PROVIDER: S-EPMC5890186 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature