Impact of five annual rounds of mass drug administration with ivermectin on onchocerciasis in Sierra Leone.

ABSTRACT:

Background

Onchocerciasis is endemic in 12 of the 14 health districts of Sierra Leone. Good treatment coverage of community-directed treatment with ivermectin was achieved between 2005 and 2009 after the 11-year civil conflict. Sentinel site surveys were conducted in 2010 to evaluate the impact of five annual rounds of ivermectin distribution.

Methods

In total, 39 sentinel villages from hyper- and meso-endemic areas across the 12 endemic districts were surveyed using skin snips in 2010. Results were analyzed and compared with the baseline data from the same 39 villages.

Results

The average microfilaridermia (MF) prevalence across 39 sentinel villages was 53.10% at baseline. The MF prevalence was higher in older age groups, with the lowest in the age group of 1-9 years

SUBMITTER: Koroma JB 

PROVIDER: S-EPMC5890354 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature