Genomic epidemiology of global VIM-producing Enterobacteriaceae.

ABSTRACT:

Background

International data on the molecular epidemiology of Enterobacteriaceae with VIM carbapenemases are limited.

Methods

We performed short read (Illumina) WGS on a global collection of 89 VIM-producing clinical Enterobacteriaceae (2008-14).

Results

VIM-producing (11 varieties within 21 different integrons) isolates were mostly obtained from Europe. Certain integrons with bla VIM were specific to a country in different species and clonal complexes (CCs) (In 87 , In 624 , In 916 and In 1323 ), while others had spread globally among various Enterobacteriaceae species (In 110 and In 1209 ). Klebsiella pneumoniae was the most common species ( n  = 45); CC147 from Greece was the most prevalent clone and contained In 590 -like integrons with four different bla VIM s.

SUBMITTER: Matsumura Y 

PROVIDER: S-EPMC5890710 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature