The development of inter-strain variation in cortical and trabecular traits during growth of the mouse lumbar vertebral body.

ABSTRACT: How cortical and trabecular bone co-develop to establish a mechanically functional structure is not well understood. Comparing early postnatal differences in morphology of lumbar vertebral bodies for three inbred mouse strains identified coordinated changes within and between cortical and trabecular traits. These early coordinate changes defined the phenotypic differences among the inbred mouse strains.

Introduction

Age-related changes in cortical and trabecular traits have been well studied; however, very little is known about how these bone tissues co-develop from day 1 of postnatal growth to establish functional structures by adulthood. In this study, we aimed to establish how cortical and trabecular tissues within the lumbar vertebral body change during growth for three inbred m

SUBMITTER: Ramcharan MA 

PROVIDER: S-EPMC5890929 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature