Predicting survival of older community-dwelling individuals according to five estimated glomerular filtration rate equations: The InChianti study.

ABSTRACT: AIMS:There is uncertainty about which estimated glomerular filtration rate eGFR equation to use in older people with respect to the prediction of prognosis. Our aim was: (i) to compare the discriminative capacity of eGFR estimated by different equations with respect to all-cause mortality; and (ii) to identify the eGFR threshold at which the risk of mortality starts to increase for each equation. METHODS:We used data from 828 community-dwelling older adults aged >65 years enrolled in the InCHIANTI study. The outcome measure was all-cause mortality at 9 years. GFR was estimated by five different equations: Chronic Kidney Disease Epidemiological Collaboration (creatinine equation [CKD-EPIcre ], and creatinine and cystatin C equation [CKD-EPIcre-cys ]), Berlin Initiative Study (BIScre and BIS

SUBMITTER: Corsonello A 

PROVIDER: S-EPMC5891358 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature