A Novel Approach to Primary Cell Culture for Octopus vulgaris Neurons.

ABSTRACT: Octopus vulgaris is a unique model system for studying complex behaviors in animals. It has a large and centralized nervous system made up of lobes that are involved in controlling various sophisticated behaviors. As such, it may be considered as a model organism for untangling the neuronal mechanisms underlying behaviors-including learning and memory. However, despite considerable efforts, Octopus lags behind its other counterparts vis-à-vis its utility in deciphering the cellular, molecular and synaptic mechanisms underlying various behaviors. This study represents a novel approach designed to establish a neuronal cell culture protocol that makes this species amenable to further exploitation as a model system. Here we developed a protocol that enables dissociation of neurons from two spe

SUBMITTER: Maselli V 

PROVIDER: S-EPMC5891582 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature