Acquisition of pluripotency in the chick embryo occurs during intrauterine embryonic development via a unique transcriptional network.

ABSTRACT:

Background

Acquisition of pluripotency by transcriptional regulatory factors is an initial developmental event that is required for regulation of cell fate and lineage specification during early embryonic development. The evolutionarily conserved core transcriptional factors regulating the pluripotency network in fishes, amphibians, and mammals have been elucidated. There are also species-specific maternally inherited transcriptional factors and their intricate transcriptional networks important in the acquisition of pluripotency. In avian species, however, the core transcriptional network that governs the acquisition of pluripotency during early embryonic development is not well understood.

Results

We found that chicken NANOG (cNANOG) was expressed in the stag

SUBMITTER: Han JY 

PROVIDER: S-EPMC5891889 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature