Validity and usefulness of a single-item measure of patient-reported bother from side effects of cancer therapy.

ABSTRACT:

Background

The improving efficacy of cancer treatment has resulted in an increasing array of treatment-related symptoms and associated burdens imposed on individuals undergoing aggressive treatment of their disease. Often, clinical trials compare therapies that have different types, and severities, of adverse effects. Whether rated by clinicians or patients themselves, it can be difficult to know which side effect profile is more disruptive or bothersome to patients. A simple summary index of bother can help to adjudicate the variability in adverse effects across treatments being compared with each other.

Methods

Across 4 studies, a total of 5765 patients enrolled in cooperative group studies and industry-sponsored clinical trials were the subjects of the current study. Pati

SUBMITTER: Pearman TP 

PROVIDER: S-EPMC5892190 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature