The Association Between Adverse Childhood Experiences and Risk of Cancer in Adulthood: A Systematic Review of the Literature.

ABSTRACT:

Context

Adverse childhood experiences (ACEs) can affect health and well-being across the life course.

Objective

This systematic review summarizes the literature on associations between ACEs and risk of cancer in adulthood.

Data sources

We searched PubMed to identify relevant publications published on or before May 31, 2015.

Study selection

We included original research quantifying the association between ACEs and adult cancer incidence. Case reports and reviews were excluded.

Data abstraction

Two reviewers independently abstracted and summarized key information (eg, ACE type, cancer type, risk estimates) from included studies and resolved all discrepancies.

Results

Twelve studies were included in the review. In studies in which ACE summary scores

SUBMITTER: Holman DM 

PROVIDER: S-EPMC5892430 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature