Dabigatran persistence and adherence in New Zealand: a nationwide retrospective observational study.

ABSTRACT: OBJECTIVE:To determine the effect of age and gender on persistence and adherence in patients taking dabigatran for atrial fibrillation. DESIGN:A retrospective observational study over 4 years using refill prescription data from the National Pharmaceutical Database. SETTING:All patients in New Zealand who received dabigatran from July 2011 to September 2015. POPULATION:43 339 people filled at least one prescription of dabigatran. MAIN OUTCOME MEASURES:The proportion of patients with good adherence (treatment available at least 80% of the time), and the proportion at risk of thrombosis (a break in treatment of more than 2 days) measured 6-monthly for 3 years. Medication persistence recorded over 3 years. RESULTS:Persistence was highest in older patients and showed a significant correlation w

SUBMITTER: Harper P 

PROVIDER: S-EPMC5892768 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature