Visceral abdominal fat measured by computer tomography as a prognostic factor for gynecological malignancies?

ABSTRACT:

Introduction

Obesity is associated with increased incidence of ovarian (OC), cervical (CC) and endometrium cancer (EC). However, the impact of body composition (BC) on overall survival (OS), especially of visceral adipose tissue (VAT) is not yet understood.

Methods

In 189 women with gynecological malignancies (31 OC, 104 CC, 54 EC, mean age 62.9y; mean BMI 26.8 kg/m²; median follow-up 30.7months) with routine staging CT-scans at baseline (mean interval: 4.3 months), densitometric quantification of total (TAT), visceral, and subcutaneous-fat-area (SAT), inter-muscular-fat-area (IMFA), and skeletal-muscle-index (SMI) was performed to analyze the impact of BC on survival.

Results

With a mean follow-up of 30.7 months 48 patients had died. We observed no signifi

SUBMITTER: Nattenmuller J 

PROVIDER: S-EPMC5893243 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature