Investigation of an isolated case of human Crimean-Congo hemorrhagic fever in Central Uganda, 2015.

ABSTRACT:

Background

Crimean-Congo hemorrhagic fever (CCHF) is the most geographically widespread tick-borne viral infection. Outbreaks of CCHF in sub-Saharan Africa are largely undetected and thus under-reported. On November 9, 2015, the National Viral Hemorrhagic Fever Laboratory at the Uganda Virus Research Institute received an alert for a suspect VHF case in a 33-year-old male who presented with VHF compatible signs and symptoms at Mengo Hospital in Kampala.

Methods

A blood sample from the suspect patient was tested by RT-PCR for CCHF and found positive. Serological testing on sequential blood specimens collected from this patient showed increasing anti-CCHFV IgM antibody titers, confirming recent infection. Repeat sampling of the confirmed case post recovery showed high titers f

SUBMITTER: Balinandi S 

PROVIDER: S-EPMC5893389 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature