Biopsy Core Features are Poor Predictors of Adverse Pathology in Men with Grade Group 1 Prostate Cancer.

ABSTRACT:

Purpose

Active surveillance is often restricted to patients with low risk prostate cancer who have 3 or fewer positive cores. We aimed to identify predictors of adverse pathology results for low risk prostate cancer treated with radical prostatectomy and determine whether a threshold number of positive cores could help the decision process for active surveillance.

Materials and methods

A total of 3,359 men with low risk prostate cancer underwent radical prostatectomy between January 2000 and August 2016. We analyzed the relationship between biopsy core features and adverse pathology at radical prostatectomy, defined as Grade Group 3 or greater, seminal vesicle invasion or lymph node involvement.

Results

Of the 171 cases (5.1%) with adverse pathology findings at radica

SUBMITTER: Audenet F 

PROVIDER: S-EPMC5893437 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature