Impact of number of co-existing rotors and inter-electrode distance on accuracy of rotor localization.

ABSTRACT:

Background

Conflicting evidence exists on the efficacy of focal impulse and rotor modulation on atrial fibrillation ablation. A potential explanation is inaccurate rotor localization from multiple rotors coexistence and a relatively large (9-11mm) inter-electrode distance (IED) of the multi-electrode basket catheter.

Methods and results

We studied a numerical model of cardiac action potential to reproduce one through seven rotors in a two-dimensional lattice. We estimated rotor location using phase singularity, Shannon entropy and dominant frequency. We then spatially downsampled the time series to create IEDs of 2-30mm. The error of rotor localization was measured with reference to the dynamics of phase singularity at the original spatial resolution (IED=1mm). IED has a sig

SUBMITTER: Aronis KN 

PROVIDER: S-EPMC5893460 | biostudies-literature | 2018 Jan - Feb

REPOSITORIES: biostudies-literature