Significant tumor shift in patients treated with stereotactic radiosurgery for brain metastasis.

ABSTRACT:

Introduction

Linac-based stereotactic radiosurgery (SRS) for brain metastases may be influenced by the time interval between treatment preparation and delivery, related to risk of anatomical changes. We studied tumor position shifts and its relations to peritumoral volume edema changes over time, as seen on MRI.

Methods

Twenty-six patients who underwent SRS for brain metastases in our institution were included. We evaluated the occurrence of a tumor shift between the diagnostic MRI and radiotherapy planning MRI. For 42 brain metastases the tumor and peritumoral edema were delineated on the contrast enhanced T1weighted and FLAIR images of both the diagnostic MRI and planning MRI examinations. Centre of Mass (CoM) shifts and tumor borders were evaluated. We evaluated the influ

SUBMITTER: Hessen ED 

PROVIDER: S-EPMC5893526 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature