Effect of the NU-AGE Diet on Cognitive Functioning in Older Adults: A Randomized Controlled Trial.

ABSTRACT: Background: Findings from animal and epidemiological research support the potential neuroprotective benefits from healthy diets. However, to establish diet-neuroprotective causal relations, evidence from dietary intervention studies is needed. NU-AGE is the first multicenter intervention assessing whether a diet targeting health in aging can counteract the age-related physiological changes in different organs, including the brain. In this study, we specifically investigated the effects of NU-AGE's dietary intervention on age-related cognitive decline. Materials and Methods: NU-AGE randomized trial (NCT01754012, clinicaltrials.gov) included 1279 relatively healthy older-adults, aged 65-79 years, from five European centers. Participants were randomly allocated into two groups:

SUBMITTER: Marseglia A 

PROVIDER: S-EPMC5893841 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature