Undiagnosed HIV infections among gay and bisexual men increasingly contribute to new infections in Australia.

ABSTRACT: INTRODUCTION:We determined the contribution of undiagnosed HIV to new infections among gay and bisexual men (GBM) over a 12-year period in Australia where there has been increasing focus on improving testing and HIV treatment coverage. METHODS:We generated annual estimates for each step of the HIV cascade and the number of new HIV infections for GBM in Australia over 2004 to 2015 using relevant national data. Using Bayesian melding we then fitted a quantitative model to the cascade and incidence estimates to infer relative transmission coefficients associated with being undiagnosed, diagnosed and not on ART, on ART with unsuppressed virus, or on ART with suppressed virus. RESULTS:Between 2004 and 2015, we estimated the percentage of GBM with HIV in Australia who were unaware of their statu

SUBMITTER: Gray RT 

PROVIDER: S-EPMC5894250 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature