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Characterisation of Newly Emerged Isolates of Classical Swine Fever Virus in China, 2014-2015.

ABSTRACT:

Introduction

In 2014-2015, the epidemic of classical swine fever (CSF) occurred in many large-scale pig farms in different provinces of China, and a subgenotype 2.1d of CSF virus (CSFV) was newly identified.

Material and methods

The phylogenetic relationship, genetic diversity, and epidemic status of the 2014-2015 CSFV isolates, 18 new CSFV isolates collected in 2015, and 43 other strains isolated in 2014-2015 were fully analysed, together with 163 CSFV reference isolates.

Results

Fifty-two 2014-2015 isolates belonged to subgenotype 2.1d and nine other isolates belonged to subgenotype 2.1b. The two subgenotype isolates showed unique molecular characteristics. Furthermore, the 2.1d isolates were found to possibly diverge from 2.1b isolates.

Conclusion

This study suggests that the Chinese CSFVs will remain pandemic.

SUBMITTER: Leng C

PROVIDER: S-EPMC5894411 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature

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Characterisation of Newly Emerged Isolates of Classical Swine Fever Virus in China, 2014-2015.

Leng Chaoliang C Zhang Hongliang H Kan Yunchao Y Yao Lunguang L Li Mingliang M Zhai Hongyue H Li Zhen Z Liu Chunxiao C Shi Hongfei H Ji Jun J Qiu Reng R Tian Zhijun Z

Journal of veterinary research 20170301 1

<h4>Introduction</h4>In 2014-2015, the epidemic of classical swine fever (CSF) occurred in many large-scale pig farms in different provinces of China, and a subgenotype 2.1d of CSF virus (CSFV) was newly identified.<h4>Material and methods</h4>The phylogenetic relationship, genetic diversity, and epidemic status of the 2014-2015 CSFV isolates, 18 new CSFV isolates collected in 2015, and 43 other strains isolated in 2014-2015 were fully analysed, together with 163 CSFV reference isolates.<h4>Resu ...[more]

PMID: 29978049

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