Comparison of Glaucoma Progression Detection by Optical Coherence Tomography and Visual Field.

ABSTRACT:

Purpose

To compare longitudinal glaucoma progression detection using optical coherence tomography (OCT) and visual field (VF).

Design

Validity assessment.

Methods

We analyzed subjects with more than 4 semi-annual follow-up visits (every 6 months) in the multicenter Advanced Imaging for Glaucoma Study. Fourier-domain optical coherence tomography (OCT) was used to map the thickness of the peripapillary retinal nerve fiber layer (NFL) and ganglion cell complex (GCC). OCT-based progression detection was defined as a significant negative trend for either NFL or GCC. VF progression was reached if either the event or trend analysis reached significance.

Results

The analysis included 356 glaucoma suspect/preperimetric glaucoma (GS/PPG) eyes and 153 perimetric glaucoma

SUBMITTER: Zhang X 

PROVIDER: S-EPMC5894829 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature