Evaluation of preventable adverse drug reactions by implementation of the nationwide network of prospective drug utilization review program in Korea.

ABSTRACT:

Background

A prospective Drug Utilization Review (DUR) program has been implemented in Korea to improve the quality and safety of medication use.

Objective

To evaluate the influence of the DUR program in reducing incidence of preventable adverse drug reactions (pADRs).

Methods

This study was performed using administrative data from the Health Insurance Review and Assessment Service (HIRA). The claims data for all adult patients with adverse drug events (ADE)-related diagnoses from 2009 to 2014 were obtained. Incidence rates of first-time and repeat pADRs prior to and after DUR program implementation were evaluated. Quarterly trends in incidence rates of overall ADE, allergic reactions, and ADRs were analyzed.

Results

Data extraction covering the period from 200

SUBMITTER: Lee J 

PROVIDER: S-EPMC5895028 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature