Herbal medicine for idiopathic central precocious puberty: A protocol for a systematic review of controlled trials.

ABSTRACT:

Background

Herbal medicine is widely used in East Asia to treat idiopathic central precocious puberty (ICPP). Most of the available clinical trials that investigated herbal medicine for ICPP have been included in this review. This systematic review will assess the efficacy and safety of herbal medicine for ICPP.

Methods

Eleven databases, including Asian databases, will be searched for studies conducted through 2018. We will include randomized controlled trials assessing herbal medicine for ICPP. The risk of bias will be evaluated using the Cochrane risk of bias assessment tool, and confidence in the cumulative evidence will be evaluated using the Grading of Recommendations Assessment, Development, and Evaluation instrument.

Ethics and dissemination

This systematic rev

SUBMITTER: Lee HL 

PROVIDER: S-EPMC5895428 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature