Risk of seizures after immunization in children with epilepsy: a risk interval analysis.

ABSTRACT:

Background

In children with epilepsy, fever and infection can trigger seizures. Immunization can also induce inflammation and fever, which could theoretically trigger a seizure. The risk of seizure after immunization in children with pre-existing epilepsy is not known. The study objective was to determine the risk of medically attended seizure after immunization in children with epilepsy < 7 years of age.

Methods

We conducted a retrospective study of children < 7 years of age with epilepsy in Nova Scotia, Canada from 2010 to 2014. Hospitalizations, emergency visits, unscheduled clinic visits, and telephone calls for seizures were extracted from medical records. Immunization records were obtained from family physicians and Public Health with informed consent. We conducted a r

SUBMITTER: Top KA 

PROVIDER: S-EPMC5896155 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature