Serum Cotinine and Hemoglobin A1c Among a National Sample of Adolescents Without Known Diabetes.

ABSTRACT:

Introduction

National data suggest tobacco smoke is positively associated with higher glycated hemoglobin (HbA1c) among adults. Our objective was to examine the association between serum cotinine and HbA1c among adolescents without known diabetes.

Methods

We assessed adolescents 12-19 years old (N = 11550) who participated in the 1999-2012 National Health and Nutrition Examination Survey. We applied sampling weights while performing multiple linear regression analyses.

Results

The prevalence of serum cotinine indicative of no tobacco smoke exposure (TSE, <0.05 ng/mL) was 43.2%, passive TSE (0.05-2.99 ng/mL) was 38.9%, and active TSE (>3 ng/mL) was 17.9% in our sample. Mean (± standard error) HbA1c in participants with no TSE was 5.16% (±0.01), passive TSE was 5.16% (±

SUBMITTER: Merianos AL 

PROVIDER: S-EPMC5896452 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature