An Exploration of the Determinants of Gestational Weight Gain in African American Women: Genetic Factors and Energy Expenditure.

ABSTRACT:

Background

Excessive gestational weight gain (GWG) has a long-term impact on women's body weight and contributes to the development of obesity in the mother and her child. Many risk factors for GWG have been identified, but to date, only 6-33.8% of the variance in GWG has been explained. The purpose of this study was to evaluate the overall variance of GWG that can be explained by including weight-adjusted resting metabolic rate (aRMR) and a genetic risk score constructed on obesity-related genes in addition to sociodemographic and lifestyle factors.

Methods

In this observational study involving 55 African American women, data collected/measured during pregnancy included sociodemographic factors, medical information, lifestyle factors, aRMR, and seven obesity-related genes.

SUBMITTER: Meng Y 

PROVIDER: S-EPMC5896561 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature