Proprioceptive and cutaneous sensations in humans elicited by intracortical microstimulation.

ABSTRACT: Pioneering work with nonhuman primates and recent human studies established intracortical microstimulation (ICMS) in primary somatosensory cortex (S1) as a method of inducing discriminable artificial sensation. However, these artificial sensations do not yet provide the breadth of cutaneous and proprioceptive percepts available through natural stimulation. In a tetraplegic human with two microelectrode arrays implanted in S1, we report replicable elicitations of sensations in both the cutaneous and proprioceptive modalities localized to the contralateral arm, dependent on both amplitude and frequency of stimulation. Furthermore, we found a subset of electrodes that exhibited multimodal properties, and that proprioceptive percepts on these electrodes were associated with higher amplitudes,

SUBMITTER: Armenta Salas M 

PROVIDER: S-EPMC5896877 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature