Ontology highlight
ABSTRACT:
SUBMITTER: Ghimire S
PROVIDER: S-EPMC5897387 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Scientific reports 20180412 1
Mouse embryonic stem cells (mESCs) exist in a naive, primed and ground state of pluripotency. While comparative analyses of these pluripotency states have been reported, the mESCs utilized originated from various genetic backgrounds and were derived in different laboratories. mESC derivation in conventional LIF + serum culture conditions is strain dependent, with different genetic backgrounds potentially affecting subsequent stem cell characteristics. In the present study, we performed a compreh ...[more]